How operations can unlock inflection points: a conversation with Janelle Muranaka

Ashoka Rajendra

Jan 22, 2025

Janelle Muranaka shares insights from her journey building multiple biotech startups from the ground up. Starting with her transition from bench scientist to operations leader, she discusses why even the smallest biotech companies need an operational framework, how to manage the tension between scientific creativity and execution, and provides concrete examples from scaling Meissa Vaccines from seed stage through multiple clinical trials.

In this interview, we cover these key topics:

  • Why operational frameworks matter from day one

  • Building and managing relationships with CROs/CDMOs

  • Scenario planning for manufacturing, clinical, and business risks

  • Creating a culture that balances innovation with execution

  • Managing competition and portfolio strategy

Whether you're a founder, scientist, or operations professional, this conversation offers practical frameworks for turning breakthrough science into successful medicines.

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